New Zealand blackcurrant extract modulates the heat shock response in men during exercise in hot ambient conditions.

ABSTRACT:

Purpose

To determine if 7d of New Zealand blackcurrant (NZBC) extract alters the heat shock, inflammatory and apoptotic response during prolonged exertional-heat stress.

Methods

Ten men (Age: 29 ± 2 years, Stature: 1.82 ± 0.02 m, Mass: 80.3 ± 2.7 kg, V̇O_2max: 56 ± 2 mL·kg^-1·min^-1) ingested two capsules of CurraNZ^™ (NZBC extract: 210 mg anthocyanins·day^-1) or PLACEBO for 7d prior to 1 h treadmill run (65% V̇O_2max) in hot ambient conditions (34 °C/40% RH). Blood samples were collected before (Pre), immediately after (Post), 1 h after (1-Post), and 4 h after (4-Post) exercise. Heat shock proteins (HSP90, HSP70, HSP32) were measured in plasma. HSP and protein markers of inflammatory capacity (TLR4, NF-κB) and apop

SUBMITTER: Conrad NJ 

PROVIDER: S-EPMC11322260 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature