Catheter ablation for atrial fibrillation and impact on clinical outcomes.

ABSTRACT:

Aims

Catheter ablation is the most effective rhythm-control option in patients with atrial fibrillation (AF) and is currently considered an option mainly for improving symptoms. We aimed to assess the impact of catheter ablation on hard clinical outcomes.

Methods and results

We performed a systematic review of randomized controlled trials (RCTs) comparing catheter ablation vs. optimized medical treatment. We searched MEDLINE, EMBASE, and CENTRAL on 8 January 2024, for trials published ≤10 years. We pooled data through risk ratio (RR) and mean differences (MDs), with 95% confidence interval (CI), and calculated the number needed to treat (NNT). Sub-group and sensitivity analyses were performed for the presence/absence of heart failure (HF), paroxysmal/persistent AF, early abl

SUBMITTER: Providencia R 

PROVIDER: S-EPMC11322836 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature