Selective sodium halide over potassium halide binding and extraction by a heteroditopic halogen bonding [2]catenane.

ABSTRACT: The synthesis and ion-pair binding properties of a heteroditopic [2]catenane receptor exhibiting highly potent and selective recognition of sodium halide salts are described. The receptor design consists of a bidentate halogen bonding donor motif for anion binding, as well as a di(ethylene glycol)-derived cation binding pocket which dramatically enhances metal cation affinity over previously reported homo[2]catenane analogues. ¹H NMR cation, anion and ion-pair binding studies reveal significant positive cooperativity between the cation and anion binding events in which cation pre-complexation to the catenane subsequently 'switches-on' anion binding. Notably, the heteroditopic catenane displayed impressive selectivity for sodium halide recognition over the corresponding potassium

SUBMITTER: Tay HM 

PROVIDER: S-EPMC11322978 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature