Spontaneous recovery from amblyopia following fellow eye vision loss: a systematic review and narrative synthesis.

ABSTRACT:

Background

The effectiveness of traditional amblyopia therapies is largely restricted to childhood. However, spontaneous recovery in adulthood is possible following vision loss in the fellow eye due to enucleation, injury, or disease. The twofold purpose of this study was (1) to define the incidence of recovery and (2) to elucidate the clinical features associated with greater amblyopic eye gains.

Methods

A systematic review of three databases yielded 24 reports containing 110 cases of patients ≥18 years old with unilateral amblyopia and vision-limiting fellow eye pathology.

Results

Our analysis revealed that 25 of 42 of adult patients (59.5%) gained ≥2 logMAR lines in the amblyopic eye after fellow eye vision loss. The degree of improvement is clinically meaningful (

SUBMITTER: Echavarri-Leet MP 

PROVIDER: S-EPMC11323063 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature