Using infection prevalence, seroprevalence and case report data to estimate chlamydial infection incidence.

ABSTRACT:

Objectives

To measure the effectiveness of chlamydia control strategies, we must estimate infection incidence over time. Available data, including survey-based infection prevalence and case reports, have limitations as proxies for infection incidence. We therefore developed a novel method for estimating chlamydial incidence.

Methods

We linked a susceptible infectious mathematical model to serodynamics data from the National Health and Nutritional Examination Survey, as well as to annual case reports. We created four iterations of this model, varying assumptions about how the method of infection clearance (via treatment seeking, routine screening or natural clearance) relates to long-term seropositivity. Using these models, we estimated annual infection incidence for women ag

SUBMITTER: Clay PA 

PROVIDER: S-EPMC11323310 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature