Exploring the clinical and biological significance of the cell cycle-related gene CHMP4C in prostate cancer.

ABSTRACT:

Background

Prostate cancer (PCa) stands as the second most prevalent malignancy impacting male health, and the disease's evolutionary course presents formidable challenges in the context of patient treatment and prognostic management. Charged multivesicular body protein 4 C (CHMP4C) participates in the development of several cancers by regulating cell cycle functions. However, the role of CHMP4C in prostate cancer remains unclear.

Methods

In terms of bioinformatics, multiple PCa datasets were employed to scrutinize the expression of CHMP4C. Survival analysis coupled with a nomogram approach was employed to probe into the prognostic significance of CHMP4C. Gene set enrichment analysis (GSEA) was conducted to interrogate the functional implications of CHMP4C. In terms of cellu

SUBMITTER: Xiao X 

PROVIDER: S-EPMC11323463 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature