The efficacy and safety of anti-vascular endothelial growth factor combined with Ahmed glaucoma valve implantation in the treatment of neovascular glaucoma: a systematic review and meta-analysis.

ABSTRACT:

Background

The intraocular injections of anti-vascular endothelial growth factor (anti-VEGF) demonstrates significant efficacy in inhibiting the formation of ocular neovascularization in neovascular glaucoma (NVG). Ahmed glaucoma valve implantation (AGVI) is extensively employed for the management of diverse glaucoma types.

Objective

To further evaluate the efficacy and safety of anti-VEGF combined with AGVI in the treatment of neovascular glaucoma.

Methods

A thorough search for randomized controlled trials (RCTs) was conducted across eight databases: PubMed, EMBASE, the Cochrane Library, Web of Science, China National Knowledge Infrastructure, Wanfang, SinoMed, and VIP. The search period was set from the inception of each database until March 2, 2024, to identify RCT

SUBMITTER: He CZ 

PROVIDER: S-EPMC11323747 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature