Choroidal Changes During and After Discontinuing Long-Term 0.01% Atropine Treatment for Myopia Control.

ABSTRACT:

Purpose

Few studies have explored choroidal changes after cessation of myopia control. This study evaluated the choroidal thickness (ChT) and choroidal vascularity index (CVI) during and after discontinuing long-term low-concentration atropine eye drops use for myopia control.

Methods

Children with progressive myopia (6-16 years; n = 153) were randomized to receive 0.01% atropine eye drops or a placebo (2:1 ratio) instilled daily over 2 years, followed by a 1-year washout (no eye drop use). Optical coherence tomography imaging of the choroid was conducted at the baseline, 2-year (end of treatment phase), and 3-year (end of washout phase) visits. The main outcome measure was the subfoveal ChT. Secondary measures include the CVI.

Results

During the treatment phase, the

SUBMITTER: Lee SS 

PROVIDER: S-EPMC11323994 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature