Oral Rinses: Some Kill and Some Cripple Candida albicans.

ABSTRACT:

Objectives

Oral healthcare professionals play a crucial role in guiding patients toward evidence-based choices among the many available oral rinses. In this study, we explored how specific oral rinse formulations affect the viability and modulate critical virulence traits of the opportunistic fungal pathogen Candida albicans.

Materials and methods

We assessed the effects of these oral rinses on the production of germ tube, production of phospholipase and hemolysin, as well as biofilm formation.

Results

We found that oral rinses containing cetylpyridinium chloride (CPC) and chlorhexidine (CHX) showed the greatest fungicidal activity with the lowest MFCs (0.38% and 0.78%, respectively). Oral rinses based on zinc chloride and sodium fluoride with Miswak bark extract (MIS

SUBMITTER: Darmani H 

PROVIDER: S-EPMC11324223 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature