Factors associated with decreased ovarian reserve in Crohn's disease: A systematic review and meta-analysis.

ABSTRACT:

Introduction

It is still unclear whether Crohn's disease (CD) might be associated with diminished ovarian reserve (OvR) and factors influencing anti-Mullerian hormone (AMH) levels in CD are poorly known.

Material and methods

We conducted a comprehensive literature search of multiple electronic databases from inception to June 2022 to identify all studies reporting AMH levels or factors associated with diminished OvR in patients with CD.

Results

Of the 48 studies identified in our search, eight (including 418 patients with CD) were finally included. The mean difference (95% confidence interval [CI]) in the AMH level between pooled CD patients and controls was -0.56 (-1.14 to 0.03) (p = 0.06). A history of CD-related surgery was not associated with a lower OvR (odds rat

SUBMITTER: Foulon A 

PROVIDER: S-EPMC11324924 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature