Identification and comparison of intestinal microbial diversity in patients at different stages of hepatic cystic echinococcosis.

ABSTRACT: There is a significant focus on the role of the host microbiome in different outcomes of human parasitic diseases, including cystic echinococcosis (CE). This study was conducted to identify the intestinal microbiome of patients with CE at different stages of hydatid cyst compared to healthy individuals. Stool samples from CE patients as well as healthy individuals were collected. The samples were divided into three groups representing various stages of hepatic hydatid cyst: active (CE1 and CE2), transitional (CE3), and inactive (CE4 and CE5). One family member from each group was selected to serve as a control. The gut microbiome of patients with different stages of hydatid cysts was investigated using metagenomic next-generation amplicon sequencing of the V3-V4 region of the 16S rRNA gene

SUBMITTER: Akhlaghi E 

PROVIDER: S-EPMC11324937 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature