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Stationary shapes of axisymmetric vesicles beyond lowest-energy configurations.

ABSTRACT: We conduct a systematic exploration of the energy landscape of vesicle morphologies within the framework of the Helfrich model. Vesicle shapes are determined by minimizing the elastic energy subject to constraints of constant area and volume. The results show that pressurized vesicles can adopt higher-energy spindle-like configurations that require the action of point forces at the poles. If the internal pressure is lower than the external one, multilobed shapes are predicted. We utilize our results to rationalize experimentally observed spindle shapes of giant vesicles in a uniform AC electric field.

SUBMITTER: Reboucas RB

PROVIDER: S-EPMC11325145 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature

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Stationary shapes of axisymmetric vesicles beyond lowest-energy configurations.

Reboucas Rodrigo B RB Faizi Hammad A HA Miksis Michael J MJ Vlahovska Petia M PM

Soft matter 20240306 10

We conduct a systematic exploration of the energy landscape of vesicle morphologies within the framework of the Helfrich model. Vesicle shapes are determined by minimizing the elastic energy subject to constraints of constant area and volume. The results show that pressurized vesicles can adopt higher-energy spindle-like configurations that require the action of point forces at the poles. If the internal pressure is lower than the external one, multilobed shapes are predicted. We utilize our res ...[more]

PMID: 38353299

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