Long-Term Survival in Patients With Advanced Melanoma.

ABSTRACT:

Importance

Long-term survival data from clinical trials show that survival curves of patients with advanced melanoma treated with immune checkpoint inhibitors (ICIs) gradually reach a plateau, suggesting that patients have a chance of achieving long-term survival.

Objective

To investigate long-term survival in patients with advanced melanoma treated with ICIs outside clinical trials.

Design, setting, and participants

Cohort study using prospectively collected data from the nationwide Dutch Melanoma Treatment Registry, including patients in the Netherlands with advanced melanoma treated with first-line ICIs from 2012 to 2019. Data were analyzed from January to September 2023.

Exposures

Patients were treated with first-line ipilimumab-nivolumab, antibodies that t

SUBMITTER: van Not OJ 

PROVIDER: S-EPMC11325208 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature