MFGM-enriched whey displays antiviral activity against common pediatric viruses in vitro.

ABSTRACT:

Background

Among the most common mucosal viral infections in infants are rotavirus, one of the main causes of severe gastroenteritis in infants and children up to 5 years, and respiratory syncytial virus (RSV), one of the leading causes of lower respiratory tract infections. Both human milk and bovine milk derived factors may provide protection against mucosal viral infections. More recently, a similar activity of milk derived proteins was suggested for SARS-CoV-2. The goal of the current study was to test antiviral activity of the bovine milkfat globule membrane (MFGM) against rotavirus, RSV and SARS-CoV-2 and to further characterize MFGM-enriched whey to identify which components in MFGM-enriched whey may contribute to the inhibitory activity.

Methods

The effects of MFGM-e

SUBMITTER: Kramer E 

PROVIDER: S-EPMC11325482 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature