From Maps to Models: A Survey on the Reliability of Small Studies of Task-Based fMRI.

ABSTRACT: Task-based functional magnetic resonance imaging is a powerful tool for studying brain function, but neuroimaging research produces ongoing concerns regarding small-sample studies and how to interpret them. Although it is well understood that larger samples are preferable, many situations require researchers to make judgments from small studies, including reviewing the existing literature, analyzing pilot data, or assessing subsamples. Quantitative guidance on how to make these judgments remains scarce. To address this, we leverage the Human Connectome Project's Young Adult dataset to survey various analyses-from regional activation maps to predictive models. We find that, for some classic analyses such as detecting regional activation or cluster peak location, studies with as few as 40 su

SUBMITTER: Sadil P 

PROVIDER: S-EPMC11326202 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature