Epinephrine Dosing Intervals Are Associated With Pediatric In-Hospital Cardiac Arrest Outcomes: A Multicenter Study.

ABSTRACT:

Objectives

Data to support epinephrine dosing intervals during cardiopulmonary resuscitation (CPR) are conflicting. The objective of this study was to evaluate the association between epinephrine dosing intervals and outcomes. We hypothesized that dosing intervals less than 3 minutes would be associated with improved neurologic survival compared with greater than or equal to 3 minutes.

Design

This study is a secondary analysis of The ICU-RESUScitation Project (NCT028374497), a multicenter trial of a quality improvement bundle of physiology-directed CPR training and post-cardiac arrest debriefing.

Setting

Eighteen PICUs and pediatric cardiac ICUs in the United States.

Patients

Subjects were 18 years young or younger and 37 weeks old or older corrected gestationa

SUBMITTER: Kienzle MF 

PROVIDER: S-EPMC11326980 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature