Intra- and inter-host origin, evolution dynamics and spatial-temporal transmission characteristics of circoviruses.

ABSTRACT:

Introduction

Since their identification in 1974, circoviruses have caused clinicopathological diseases in various animal species, including humans. However, their origin, transmission, and genetic evolution remain poorly understood.

Methods

In this study, the genome sequences of circovirus were obtained from GenBank, and the Bayesian stochastic search variable selection algorithm was employed to analyzed the evolution and origin of circovirus.

Results

Here, the evolutionary origin, mode of transmission, and genetic recombination of the circovirus were determined based on the available circovirus genome sequences. The origin of circoviruses can be traced back to fish circovirus, which might derive from fish genome, and human contributes to transmission of fish circovir

SUBMITTER: Cui Y 

PROVIDER: S-EPMC11327096 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature