De novo construction of amine-functionalized metal-organic cages as heterogenous catalysts for microflow catalysis.

ABSTRACT: Microflow catalysis is a cutting-edge approach to advancing chemical synthesis and manufacturing, but the challenge lies in developing efficient and stable multiphase catalysts. Here we showcase incorporating amine-containing metal-organic cages into automated microfluidic reactors through covalent bonds, enabling highly continuous flow catalysis. Two Fe₄L₄ tetrahedral cages bearing four uncoordinated amines were designed and synthesized. Post-synthetic modifications of the amine groups with 3-isocyanatopropyltriethoxysilane, introducing silane chains immobilized on the inner walls of the microfluidic reactor. The immobilized cages prove highly efficient for the reaction of anthranilamide with aldehydes, showing superior reactivity and recyclability relative to free c

SUBMITTER: Li Y 

PROVIDER: S-EPMC11327339 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature