Predictors of occult metastases in potentially Resectable pancreatic ductal adenocarcinoma.

ABSTRACT:

Background

Patients with resectable (R) or borderline resectable (BR) pancreatic ductal adenocarcinoma (PDAC) sometimes show unexpected liver, peritoneal, and para-aortic lymph node metastases intraoperatively. Despite radical pancreatectomy, a nonnegligible number of patients relapse within 6 months after surgery. The aim of this study was to identify the preoperative predictors of occult metastases (OM), defined as intraoperative distant metastases or within 6 months after pancreatectomy.

Materials and methods

This study included patients with R and BR PDAC who underwent curative-intent pancreatectomy or staging laparoscopy between 2006 and 2021. Multivariate logistic regression and Cox hazard analyses were performed to identify the preoperative predictors of OM and to ass

SUBMITTER: Murakami T 

PROVIDER: S-EPMC11327574 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature