Exploring the association between metabolic syndrome, its components and subsequent cancer incidence: A cohort study in Catalonia.

ABSTRACT:

Background

Metabolic syndrome (MS) has emerged as a significant global health concern. The relationship between MS and the risk of cancer doesn't seem clear, whether examining by components or in combination. The objective of this study is to examine the relationship between MS, its components, and the overall risk of cancer, including the risk of 13 specific cancer types.

Methods

We included 3,918,781 individuals aged 40 years or older sourced from the SIDIAP database between 2008 and 2017. Cox models were employed with MS components and their combinations. A subsample was created using a matched cohort (by age and sex). Incidence curves were computed to determine the time elapsed between the date of having 1-5 MS components and cancer incidence, compared to matched partici

SUBMITTER: Lopez-Jimenez T 

PROVIDER: S-EPMC11327772 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature