Life-threatening amiodarone-induced thyrotoxicosis - Personalized approach to radical treatment.

ABSTRACT:

Objective

Amiodarone is an iodine-rich molecule and an effective antiarrhythmic drug. It is a first-line treatment for patients with life-threatening ventricular arrhythmias and for prevention in patients at high risk. The use of amiodarone may cause serious adverse effects such as pharmacotherapy-resistant, life-threatening amiodarone-induced thyrotoxicosis (AIT)leading to rapid deterioration of the patient's condition.According to the European Thyroid Association (ETA) guidelines, emergency thyroidectomy is the first-line treatment option in these cases. ; however, is not always feasible in the clinical setting due to the high anesthetic risk.We aimed to assess the clinical course and results of urgent thyroidectomy and 131-I therapy in patients with severe AIT with worsening of

SUBMITTER: Opalinska M 

PROVIDER: S-EPMC11327811 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature