Antithrombin III Levels and Outcomes Among Patients With Trauma.

ABSTRACT:

Importance

Patients with trauma exhibit a complex balance of coagulopathy manifested by both bleeding and thrombosis. Antithrombin III is a plasma protein that functions as an important regulator of coagulation. Previous studies have found a high incidence of antithrombin III deficiency among patients with trauma.

Objective

To assess whether changes in antithrombin III activity are associated with thrombohemorrhagic complications among patients with trauma.

Design, setting, and participants

This cohort study was conducted from December 2, 2015, to March 24, 2017, at a level I trauma center. A total of 292 patients with trauma were followed up from their arrival through 6 days from admission. Data, including quantification of antithrombin III activity, were collected f

SUBMITTER: Farrell DH 

PROVIDER: S-EPMC11327888 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature