Building a Simplistic Automatic Extruder: Instrument Development Opportunities for the Laboratory.

ABSTRACT: This work presents an automatic extruder as a research experience for undergraduate students. The system offers a user-friendly approach to preparing vesicles, such as liposomes or polymersomes, with a defined size and polydispersity-properties crucial for research in biology and macromolecules. It comprises two syringe pumps connected by a membrane filter. The setup is controlled by software. Compared to manual extrusion, this automated system provides advantages, such as precisely controlled variables. The project describes a tool to enhance undergraduate learning in science and engineering laboratories. Building an automatic extruder serves as a simplified model of a complex industrial process. It offers a clear advantage: automating a well-understood manual extrusion process. To make t

SUBMITTER: Klisch S 

PROVIDER: S-EPMC11327960 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature