A comparative analysis of preclinical computed tomography radiomics using cone-beam and micro-computed tomography scanners.

ABSTRACT:

Background and purpose

Radiomics analysis extracts quantitative data (features) from medical images. These features could potentially reflect biological characteristics and act as imaging biomarkers within precision medicine. However, there is a lack of cross-comparison and validation of radiomics outputs which is paramount for clinical implementation. In this study, we compared radiomics outputs across two computed tomography (CT)-based preclinical scanners.

Materials and methods

Cone beam CT (CBCT) and µCT scans were acquired using different preclinical CT imaging platforms. The reproducibility of radiomics features on each scanner was assessed using a phantom across imaging energies (40 & 60 kVp) and segmentation volumes (44-238 mm³). Retrospective mouse scans

SUBMITTER: Brown KH 

PROVIDER: S-EPMC11328005 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature