Characteristics of Long-Term Survivors With EGFR-Mutant Metastatic NSCLC.

ABSTRACT:

Introduction

Characteristics of long-term survivors in EGFR-mutant (EGFRm) NSCLC are not fully understood. This retrospective analysis evaluated a multi-institution cohort of patients with EGFRm NSCLC treated in the pre-osimertinib era and sought to describe characteristics of long-term survivors.

Methods

Clinical characteristics and outcomes were abstracted from the electronic medical records of patients with EGFRm metastatic NSCLC who started first-line therapy before 2015. Demographics and comutations were compared between greater than or equal to 5-year survivors and less than 5-year survivors. Multivariable Cox proportional hazard and logistic regression models were used to evaluate factors associated with survival and the odds of death within 5 years, respectively.

SUBMITTER: Tompkins W 

PROVIDER: S-EPMC11328087 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature