Global trends in incidence and prevalence of achalasia, 1925-2021: A systematic review and meta-analysis.

ABSTRACT:

Background

Achalasia poses a significant socioeconomic burden, yet global trends remain undocumented. This study aims to describe the worldwide trends in the incidence and prevalence of achalasia from 1925 to 2021 and explore their correlation with various factors through a comprehensive systematic review.

Methods

We searched the PubMed/MEDLINE, Embase, and Cochrane databases from inception to 30 June 2023, to identify studies reporting the incidence or prevalence of achalasia in the general population. This study utilized pooled estimates with 95% confidence intervals (CI) to estimate the incidence and prevalence of achalasia, and conducted various subgroup analyses.

Results

A total of 26 eligible studies covering approximately 269 million participants and 20,873 pat

SUBMITTER: Lee K 

PROVIDER: S-EPMC11328114 | biostudies-literature | 2024 May

REPOSITORIES: biostudies-literature