Efficacy of personalized repetitive transcranial magnetic stimulation based on functional reserve to enhance ambulatory function in patients with Parkinson's disease: study protocol for a randomized controlled trial.

ABSTRACT:

Background

Repetitive transcranial magnetic stimulation (rTMS) is one of the non-invasive brain stimulations that modulate cortical excitability through magnetic pulses. However, the effects of rTMS on Parkinson's disease (PD) have yielded mixed results, influenced by factors including various rTMS stimulation parameters as well as the clinical characteristics of patients with PD. There is no clear evidence regarding which patients should be applied with which parameters of rTMS. The study aims to investigate the efficacy and safety of personalized rTMS in patients with PD, focusing on individual functional reserves to improve ambulatory function.

Methods

This is a prospective, exploratory, multi-center, single-blind, parallel-group, randomized controlled trial. Sixty patien

SUBMITTER: Yun SJ 

PROVIDER: S-EPMC11328369 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature