Sex- and strain-dependent effects of ageing on sleep and activity patterns in Drosophila.

ABSTRACT: The fruit fly Drosophila is a major discovery platform in the biology of ageing due to its balance of relatively short lifespan and relatively complex physiology and behaviour. Previous studies have suggested that some important phenotypes of ageing, for instance increasingly fragmented sleep, are shared from humans to Drosophila and can be useful measures of behavioural change with age: these phenotypes therefore hold potential as readouts of healthy ageing for genetic or pharmacological interventions aimed at the underpinning biology of ageing. However, some age-related phenotypes in Drosophila show differing results among studies, leading to questions regarding the source of discrepancies among experiments. In this study, I have tested females and males from three common laboratory stra

SUBMITTER: Woodling N 

PROVIDER: S-EPMC11329114 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature