Maintaining a gluten-free diet is associated with quality of life in youths with type 1 diabetes and celiac disease.

ABSTRACT:

Aim

Conflicting findings have been reported on whether in youths, the double diagnosis of type 1 diabetes (T1D) and celiac disease (CD) substantially impacts quality of life QoL, compared to subjects with T1D only.

Methods

In this study, 86 youths with double diagnosis and their parents were compared to 167 subjects with T1D only. QoL was assessed through the KINDL questionnaire. Anti-tissue transglutaminase antibodies and dietary interviews evaluated the degree of maintaining a gluten-free diet (GFD).

Results

We found that having CD in addition to T1D has little effect on overall QoL. However, analysis of the degree of maintaining GFD revealed significantly lower total QoL scores in groups with T1D + CD not strictly maintaining GFD compared to T1D only (p = 0.0014).

SUBMITTER: Franceschi R 

PROVIDER: S-EPMC11329396 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature