Understanding Anxiety in Cervical Dystonia: An Imaging Study.

ABSTRACT:

Background

Anxiety may precede motor symptoms in cervical dystonia (CD) and is associated with an earlier onset of dystonia. Our understanding of anxiety in CD is inadequate.

Objective

To investigate brain networks associated with anxiety in CD.

Methods

Twenty-six subjects with idiopathic CD underwent MRI Brain without contrast. Correlational tractography was derived using Diffusion MRI connectometry. Quantitative Anisotropy (QA) was used in deterministic diffusion fiber tracking. Correlational tractography was then used to correlate QA with State-Trait Anxiety Inventory (STAI) state (STAI-S) and trait (STAI-T) subscales.

Results

Connectometry analysis showed direct correlation between state anxiety and QA in tracts from amygdala to thalamus/ pulvinar bilateral

SUBMITTER: Mahajan A 

PROVIDER: S-EPMC11329561 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature