Relationship between chocolate consumption and overall and cause-specific mortality, systematic review and updated meta-analysis.

ABSTRACT: Chocolate is a rich dietary source of various bioactive flavonoid compounds. Despite being one of the most popular foods worldwide, the association between chocolate consumption and long-term mortality remains unclear. The objective of this study is to determine the associations between chocolate consumption and long-term overall and cause-specific mortality, to evaluate dose-response and potential mediators, and to conduct an updated meta-analysis based on prospective cohort studies. We performed a prospective analysis in the Alpha-Tocopherol, Beta-Carotene cancer prevention (ATBC) Study with a total of 27,111 men who were recruited between 1985 and 1988 and followed through 2015. Exposure data of daily chocolate consumption was obtained from validated baseline food frequency questionnair

SUBMITTER: Zhao B 

PROVIDER: S-EPMC11329947 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature