Cortical atrophy patterns in myelin oligodendrocyte glycoprotein antibody-associated disease.

ABSTRACT:

Objectives

Global brain volume changes in patients with myelin oligodendrocyte glycoprotein antibody-associated disease compared with healthy controls (HC) could be revealed by magnetic resonance imaging, but specific atrophy patterns of cortical structures and relation to cognitive impairment are not yet comprehensively known. Thus, we aimed to investigate cortical thickness differences in patients with myelin oligodendrocyte glycoprotein antibody-associated disease compared with HC.

Methods

3-Tesla brain magnetic resonance imaging was performed in 23 patients with myelin oligodendrocyte glycoprotein antibody-associated disease and 49 HC for voxel-wise group comparisons and neuropsychological testing in patients. Surface-based morphometry with region of interest-based surfa

SUBMITTER: Schneider R 

PROVIDER: S-EPMC11330211 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature