Muscle hypertrophy following acquired neurogenic injury: systematic review and analysis of existing literature.

ABSTRACT:

Objectives

Neurogenic muscle hypertrophy (NMH) is a rare condition characterized by focal muscle hypertrophy caused by chronic partial nervous injury. Given its infrequency, underlying mechanisms remain poorly understood. Inspired by two clinical cases, we conducted a systematic review to gain insights into the different aspects of NMH.

Methods

We systematically searched online databases up until May 30, 2023, for reports of muscle hypertrophy attributed to acquired neurogenic factors. We conducted an exploratory analysis to identify commonly associated features. We also report two representative clinical cases.

Results

Our search identified 63 reports, describing 93 NMH cases, to which we added our two cases. NMH predominantly affects patients with compressive radicu

SUBMITTER: Strano CM 

PROVIDER: S-EPMC11330231 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature