PMiSLocMF: predicting miRNA subcellular localizations by incorporating multi-source features of miRNAs.

ABSTRACT: The microRNAs (miRNAs) play crucial roles in several biological processes. It is essential for a deeper insight into their functions and mechanisms by detecting their subcellular localizations. The traditional methods for determining miRNAs subcellular localizations are expensive. The computational methods are alternative ways to quickly predict miRNAs subcellular localizations. Although several computational methods have been proposed in this regard, the incomplete representations of miRNAs in these methods left the room for improvement. In this study, a novel computational method for predicting miRNA subcellular localizations, named PMiSLocMF, was developed. As lots of miRNAs have multiple subcellular localizations, this method was a multi-label classifier. Several properties of miRNA, s

SUBMITTER: Chen L 

PROVIDER: S-EPMC11330342 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature