Weight reduction and the impact on apnea-hypopnea index: A systematic meta-analysis.

ABSTRACT: Obstructive sleep apnea (OSA) is strongly associated with obesity. While the relationship between weight reduction and apnea-hypopnea index improvement has been documented, to our knowledge, it has not been quantified adequately. Therefore, this study aimed to quantify the relationship between weight reduction and AHI change.

Methods

A systematic literature search was performed using meta-analyses (PRISMA) guidelines for studies reporting AHI and weight loss in people with obesity/overweight and OSA between 2000 and 2023. A linear and quadratic model (weighted by treatment arm sample size) predicted percent change from baseline AHI against mean percent change from baseline weight. The quadratic term was statistically significant (P < 0.05), so the quadratic model (with 95 % predicti

SUBMITTER: Malhotra A 

PROVIDER: S-EPMC11330732 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature