A neural basis for learning sequential memory in brain loop structures.

ABSTRACT:

Introduction

Behaviors often involve a sequence of events, and learning and reproducing it is essential for sequential memory. Brain loop structures refer to loop-shaped inter-regional connection structures in the brain such as cortico-basal ganglia-thalamic and cortico-cerebellar loops. They are thought to play a crucial role in supporting sequential memory, but it is unclear what properties of the loop structure are important and why.

Methods

In this study, we investigated conditions necessary for the learning of sequential memory in brain loop structures via computational modeling. We assumed that sequential memory emerges due to delayed information transmission in loop structures and presented a basic neural activity model and validated our theoretical considerations wit

SUBMITTER: Sihn D 

PROVIDER: S-EPMC11330804 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature