Narrative review of indication and management of induction therapy for thymic epithelial tumors.

ABSTRACT:

Background and objective

Thymic epithelial tumors (TETs) are rare and originate from the thymus. Thymomas and thymic carcinomas are the most common types of TETs. Of the two, thymomas tend to have a better prognosis and are typically localized, while thymic carcinomas have a worse prognosis and are more likely to spread. The Masaoka-Koga staging system is commonly used to determine the stage of TETs. Complete resection is the preferred treatment option, but treating locally advanced TETs can be challenging due to the invasion of surrounding structures. In such cases, induction therapy is administered to downstage the tumors and enable complete resection. We conducted this narrative review to evaluate the current progress in induction treatment for locally advanced TETs.

Methods<

SUBMITTER: Ajimizu H 

PROVIDER: S-EPMC11330911 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature