General theory for localizing the where and when of entropy production meets single-molecule experiments.

ABSTRACT: The laws of thermodynamics apply to biophysical systems on the nanoscale as described by the framework of stochastic thermodynamics. This theory provides universal, exact relations for quantities like work, which have been verified in experiments where a fully resolved description allows direct access to such quantities. Complementary studies consider partially hidden, coarse-grained descriptions, in which the mean entropy production typically is not directly accessible but can be bounded in terms of observable quantities. Going beyond the mean, we introduce a fluctuating entropy production that applies to individual trajectories in a coarse-grained description under time-dependent driving. Thus, this concept is applicable to the broad and experimentally significant class of driven systems

SUBMITTER: Degunther J 

PROVIDER: S-EPMC11331124 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature