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Early life stress and iron metabolism in developmental psychoneuroimmunology.


ABSTRACT: An estimated 250 million children face adverse health outcomes from early life exposure to severe or chronic social, economic, and nutritional adversity, highlighting/emphasizing the pressing concern about the link between ELS and long-term implications on mental and physical health. There is significant overlap between populations experiencing high levels of chronic stress and those experiencing iron deficiency, spotlighting the potential role of iron as a key mediator in this association. Iron, an essential micronutrient for brain development and immune function, is often depleted in stress conditions. Iron deficiency among the most common nutrient deficiencies in the world. Fetal and infant iron status may thus serve as a crucial intermediary between early chronic psychological stress a

SUBMITTER: Reid BM 

PROVIDER: S-EPMC11331713 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature