Intranasal oxytocin interacts with testosterone reactivity to modulate parochial altruism.

ABSTRACT: The neuropeptide hormone oxytocin and the steroid hormone testosterone have received attention as modulators of behavior in the context of intergroup conflict. However, to date, their interactive effect has yet to be tested. Here, in a double-blind placebo-control design, 204 participants (102 female participants) self-administrated oxytocin or placebo and completed an experimental economic game modeling intergroup conflict. Salivary testosterone (n = 192) was measured throughout the task to assess endogenous reactivity. As a caveat, even at this sample size, our derived power to detect small effects for 2- and 3-way interactions was relatively low. For male participants, changes in testosterone predicted willingness to sacrifice investments for the betterment of the group. Intranasal admi

SUBMITTER: Cherki BR 

PROVIDER: S-EPMC11332015 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature