Excess weight, weight gain, and prostate cancer risk and prognosis: the PROCA-life study.

ABSTRACT:

Background

Studies of excess weight and weight changes throughout adult life for prostate cancer (PCa) risk and prognosis have shown inconsistent results.

Methods

In a population-based cohort, the Prostate Cancer Study throughout life (PROCA-life), 16,960 healthy men from the prospective cohort Tromsø Study (1994-2016) were included. Body mass index (BMI) and weight were measured at all four attendings, and weight change was calculated as the difference between the first and last of either Tromsø4, Tromsø5 or Tromsø6. Overall, 904 men developed PCa during 16 years of follow-up, and Poisson regression with fractional polynomials was used to investigate trends in incidence. Cox proportional hazard and logistic regression models were used to study associations between measureme

SUBMITTER: Stoyten M 

PROVIDER: S-EPMC11332472 | biostudies-literature | 2024 Apr

REPOSITORIES: biostudies-literature