Spot-scanning proton therapy for early breast cancer in free breathing versus deep inspiration breath-hold.

ABSTRACT:

Background and purpose

Proton therapy for breast cancer is usually given in free breathing (FB). With the use of deep inspiration breath-hold (DIBH) technique, the location of the heart is displaced inferiorly, away from the internal mammary nodes and, thus, the dose to the heart can potentially be reduced. The aim of this study was to explore the potential benefit of proton therapy in DIBH compared to FB for highly selected patients to reduce exposure of the heart and other organs at risk. We aimed at creating proton plans with delivery times feasible with treatment in DIBH.

Material and methods

Sixteen patients with left-sided breast cancer receiving loco-regional proton therapy were included. The FB and DIBH plans were created for each patient using spot-scanning proton t

SUBMITTER: Stick LB 

PROVIDER: S-EPMC11332550 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature