Risk of extended viral shedding of Omicron BA.2 in Shanghai: Implications for vaccination strategy optimization.

ABSTRACT:

Background

In late March 2022, an outbreak of coronavirus disease 2019 (COVID-19) caused by the Omicron BA.2 strain occurred in Shanghai, China. This retrospective study aimed to investigate the clinical characteristics, laboratory parameters, and vaccine protectiveness related to this disease in China.

Methods

We conducted a single-center retrospective study on 735 patients with COVID-19 hospitalized from March 17 to May 14, 2022. Clinical characteristics were analyzed based on vaccination status and viral shedding time (VST). The least absolute shrinkage and selection operator (LASSO) regression and 5-fold cross-validation were applied to screen factors linked to the rate of the VST. Generalized linear models were further applied to estimate the odds ratios for factors inf

SUBMITTER: Huang J 

PROVIDER: S-EPMC11332869 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature