Liver dysfunction on admission worsens clinical manifestations and outcomes of coronavirus disease 2019.

ABSTRACT:

Background

Liver dysfunction was common in coronavirus disease 2019 (COVID-19), but its association with clinical features and poor prognosis has not been fully delineated. Our study aimed to determine the role of liver dysfunction in COVID-19 and understand the predictors for worse outcomes in patients with liver injury.

Methods

We conducted this multicenter, retrospective study in five designated hospitals for COVID-19 management. Laboratory-confirmed COVID-19 patients were enrolled and classified into the normal live function group and liver dysfunction group according to liver enzymes, bilirubin, and albumin on admission, respectively. Data of baseline, clinical manifestations, and outcomes were collected and compared in the paired groups.

Results

Of the 649 inclu

SUBMITTER: Lu F 

PROVIDER: S-EPMC11332890 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature