Acoustically evoked K-complexes together with sleep spindles boost verbal declarative memory consolidation in healthy adults.

ABSTRACT: Over the past decade, phase-targeted auditory stimulation (PTAS), a neuromodulation approach which presents auditory stimuli locked to the ongoing phase of slow waves during sleep, has shown potential to enhance specific aspects of sleep functions. However, the complexity of PTAS responses complicates the establishment of causality between specific electroencephalographic events and observed benefits. Here, we used down-PTAS during sleep to specifically evoke the early, K-complex (KC)-like response following PTAS without leading to a sustained increase in slow-wave activity throughout the stimulation window. Over the course of two nights, one with down-PTAS, the other without, high-density electroencephalography (hd-EEG) was recorded from 14 young healthy adults. The early response exhibit

SUBMITTER: Leach S 

PROVIDER: S-EPMC11333484 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature