Interpregnancy interval and adverse perinatal outcomes: A within-individual comparative method.

ABSTRACT:

Background and aim

Previously observed associations between interpregnancy interval (IPI) and perinatal outcomes using a between-individual method may be confounded by unmeasured maternal factors. This study aims to examine the association between IPI and adverse perinatal outcomes using within-individual comparative analyses.

Methods

We studied 10,647 individuals from the National Institute of Child Health and Human Development Consecutive Pregnancies Study in Utah with ≥3 liveborn singleton pregnancies. We matched two IPIs per individual and used conditional logistic regression to examine the association between IPI and adverse perinatal outcomes, including preterm birth (PTB, <37 weeks' gestation), small-for-gestational-age (SGA, <10th percentile of sex-specific birthweig

SUBMITTER: Sevoyan M 

PROVIDER: S-EPMC11333538 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature