Dramatic improvements in outcome following pancreatoduodenectomy for pancreatic and periampullary cancers.

ABSTRACT:

Background

Pancreatoduodenectomy is the only cure for cancers of the pancreas and the periampullary region but has considerable operative complications and uncertain prognosis. Our goal was to analyse temporal improvements and provide contemporary population-based benchmarks for outcomes following pancreatoduodenectomy.

Methods

We empanelled a cohort comprising all patients in Sweden with pancreatic or periampullary cancer treated with pancreatoduodenectomy from 1964 to 2016 and achieved complete follow-up through 2016. We analysed postoperative deaths and disease-specific net survival.

Results

We analysed 5923 patients with cancer of the pancreas (3876), duodenum (444), bile duct (504), or duodenal papilla (963) who underwent classic (3332) or modified (1652) Whipple

SUBMITTER: Xu H 

PROVIDER: S-EPMC11333598 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature