Internal Psychometric Validation of an International Burden of Illness Survey for Idiopathic Multicentric Castleman Disease.

ABSTRACT:

Introduction

Idiopathic multicentric Castleman disease (iMCD) is a rare, chronic, debilitating lymphoproliferative disorder where the mainstay of treatment is symptom management. Our recent international patient survey showed that patients with iMCD have a high symptom burden that has a significant negative patient-reported impact on several aspects of daily life. As part of our ongoing work towards the development of an iMCD symptom burden scale, assessing the survey's psychometric properties is a critical step in understanding its adequacy, relevance, and usefulness. As iMCD is a rare disease, there are challenges to conducting such psychometric analyses which we describe.

Methods

As part of the exploratory psychometric analysis, three a priori hypothesis sets (HS) were ge

SUBMITTER: Franklin M 

PROVIDER: S-EPMC11333659 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature