Association of olfactory and cognitive function test scores with hippocampal and amygdalar grey matter volume: a cross-sectional study.

ABSTRACT: Few population-based studies including younger adults have examined the potential of olfactory function tests to capture the degree of atrophy in memory-associated brain regions, which cannot be adequately explained by cognitive function tests screening for cognitive impairment. This population-based study investigated associations between high-resolution olfactory test data with few odours and grey matter volumes (GMVs) of the left and right hippocampi, amygdala, parahippocampi, and olfactory cortex, while accounting for differences in cognitive decline, in 1444 participants (aged 31-91 years). Regression analyses included intracranial volume (ICV)-normalised GMVs of eight memory-related regions as objective variables and age, sex, education duration, smoking history, olfaction test score

SUBMITTER: Sato S 

PROVIDER: S-EPMC11333722 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature