Impact of diet change on the gut microbiome of common marmosets (<i>Callithrix jacchus</i>).

ABSTRACT: Gastrointestinal diseases are the most frequently reported clinical problems in captive common marmosets (Callithrix jacchus), often affecting the health and welfare of the animal and ultimately their use as a research subject. The microbiome has been shown to be intimately connected to diet and gastrointestinal health. Here, we use shotgun metagenomics and untargeted metabolomics in fecal samples of common marmosets collected before, during, and after a dietary transition from a biscuit to a gel diet. The overall health of marmosets, measured as weight recovery and reproductive outcome, improved after the diet transition. Moreover, each marmoset pair had significant shifts in the microbiome and metabolome after the diet transition. In general, we saw a decrease in Escherichia co

SUBMITTER: Tang-Wing C 

PROVIDER: S-EPMC11334461 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature